MS4A2 CLIA Kit for Human(Homo sapiens) | EIAab.comMS4A2 CLIA Kit for Human(Homo sapiens)

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MS4A2 (Gene name),

High affinity immunoglobulin epsilon receptor subunit beta (Protein name ), FCERB_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

MS4A2(APY;FCER1B;IGER);

Protein name:

High affinity immunoglobulin epsilon receptor subunit beta(FcERI);

Alternative:

IgE Fc receptor subunit beta;Fc epsilon receptor I beta-chain;Membrane-spanning 4-domains subfamily A member 2;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Tetramer of an alpha chain, a beta chain, and two disulfide linked gamma chains. Binds LILRB1. Interacts with FGR and FES/FPS.

Function:

High affinity receptor that binds to the Fc region of immunoglobulins epsilon. Aggregation of FCER1 by multivalent antigens is required for the full mast cell response, including the release of preformed mediators (such as histamine) by degranulation and de novo production of lipid mediators and cytokines. Also mediates the secretion of important lymphokines. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators responsible for the manifestations of allergy.

Subcellular Location:

Membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

244

Sequence:

50:

100:

150:

200:

244:

ICGAGEELKG | NKVPEDRVYE | ELNIYSATYS | ELEDPGEMSP | PIDL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

hsa:2206

MIM:

147138

String:

Q01362

STRING:

9606.ENSP00000278888

Pfam:

PF04103

UniGene:

Hs.386748

Uniprot:

Q01362

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ELISA Kit for Human FcERI

Cat.:

E1891r

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Manual:

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Packing:

96T

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ELISA Kit for Human FcERI

Cat.:

E1891m

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MSDS:

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Packing:

96T

ELISA Kit for Human FcERI

Cat.:

E1891h

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96T

CLIA Kit for Human FcERI

Cat.:

U1891m

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MSDS:

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Packing:

96T

CLIA Kit for Human FcERI

Cat.:

U1891h

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MSDS:

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Packing:

96T

CLIA Kit for Human FcERI

Cat.:

U1891r

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human FcERI

Cat.:

P1891Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human FcERI

Cat.:

P1891Rb-r

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40ug/0.2ml

Polyclonal Antibody for Human FcERI

Cat.:

P1891Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human FcERI

Protein for Human FcERI

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"The gene and cDNA for the human high affinity immunoglobulin E receptor beta chain and expression of the complete human receptor."
Kuester H. , Zhang L. , Brini A.T. , Macglashan D.W. , Kinet J.-P.
J. Biol. Chem.267:12782-12787(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
2.

"Determination of the sequence coding for the beta subunit of the human high-affinity IgE receptor."
Maekawa K. , Imagawa N. , Tanaka Y. , Harada S.
FEBS Lett.302:161-165(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
3.

"Regulation of human FcepsilonRI beta chain gene expression by Oct-1."
Akizawa Y. , Nishiyama C. , Hasegawa M. , Maeda K. , Nakahata T. , Okumura K. , Ra C. , Ogawa H.
Int. Immunol.15:549-556(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Lung.
5.

"A new variant of the beta subunit of the high-affinity receptor for immunoglobulin E (Fc epsilon RI-beta E237G): associations with measures of atopy and bronchial hyper-responsiveness."
Hill M.R. , Cookson W.O.
Hum. Mol. Genet.5:959-962(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT GLY-237
6.

"Association between atopic asthma and a coding variant of Fc-epsilon-RI-beta in a Japanese population."
Shirakawa T. , Mao X.-Q. , Sasaki S. , Enomoto T. , Kawai M. , Morimoto K. , Hopkin J.
Hum. Mol. Genet.5:1129-1130(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT GLY-237
7.

Shirakawa T. , Mao X.-Q. , Sasaki S. , Enomoto T. , Kawai M. , Morimoto K. , Hopkin J.
Hum. Mol. Genet.5:2068-2068(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM

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